CARELL GROUP Research – Nucleic Acid Technology

Research on non-canonical bases requires the development of new sequencing- and mass spectrometry-based quantification technologies.

The Carell group developed the Cu(I)-catalyzed click reaction for the post-synthetic high-density modification of DNA, which allows the spin-off Baseclick GmbH to develop new cell proliferation assays and chemistry for efficient and cost-effective next generation sequencing.

The Carell technology is now operating in the third-generation sequencers of Pacific Bioscience and Roche Sequencing.

New tools for the high-density labelling of DNA. RNA dendrimer to stir cellular development.