CARELL GROUP – Publications

308

L. Montiel, F. Spanda, S. Bessinovo, A. Crisp, C. Berger, S. Wiedemann, T. Carell, T. Frischmuth

J. Carbohyd. Chem., 2024, 10.1080/07328303.2024.2418524

"Synthesis and validation of clickable multimeric mannose ligands for dendritic cell targeting"

 Link to publication

307

H. Sahin, R. Salehi, S. Islam, M. Müller, P. Giehr, Thomas Carell

Angew. Chem. Int. Ed. 2024, 10.1002/anie.202418500

"Robust Bisulfite-Free Single-Molecule Real-Time Sequencing of Methyldeoxycytidine Based on a Novel hpTet3 Enzyme"

 Link to publication

306

A.-L.J. Halbritter, Y.V. Gärtner, J. Nabiev, F. Hernichel, G. Ganazzoli, D. Özdemir, A. Pappa, S. Veth, S. Stazzoni, M. Müller, V. Hornung, T. Carell

Angew. Chem. Int. Ed. 2024, 10.1002/anie.202416353

"A Phosphotriester-Masked Dideoxy-cGAMP Derivative as a Cell-Permeable STING Agonist"

 Link to publication

305

R. Yehuda, I. Dromi, Y. Levin, T. Carell, N. Geacintov and Z. Livneh

Oncogene 2024, 10.1038/s41388-024-03192-0

"Hypoxia-dependent recruitment of error-prone DNA polymerases to genome replication"

 Link to publication

304

I. Mejdrova, E. Węgrzyn, T. Carell

Chem. - Asian J. 2024, 10.1002/asia.202401074

"Step-by-Step Towards Biological Homochirality – from Prebiotic Randomness To Perfect Asymmetry"

Link to publication

303

C. Steinek, M. Guirao-Ortiz, G. Stumberger, A.J. Tölke, D. Hörl, T. Carell, H. Harz, H. Leonhardt

Cells Rep. Methods 2024, 10.1016/j.crmeth.2024.100840

"Generation of densely labeled oligonucleotides for the detection of small genomic elements"

 Link to publication

302

E. Węgrzyn, I. Mejdrova, T. Carell  

Chem. Sci. 2024, 10.1039/d4sc03384a

"Gradual evolution of a homo-L-peptide world on homo-D-configured RNA and DNA"

 Link to publication

301

M. Bérouti, K. Lammens, M. Heiss, L. Hansbauer, S. Bauernfried, J. Stöckl, F. Pinci, I. Piseddu, W. Greulich, M. Wang, C. Jung, T. Fröhlich, T. Carell, K.P. Hopfner, V. Hornung

Immunity 2024, 10.1016/j.immuni.2024.04.010

"Lysosomal endonuclease RNase T2 and PLD exonucleases cooperatively generate RNA ligands for TLR7 activation"

 Link to publication

300

A.J. Tölke, J.F. Gaisbauer, Y.V. Gärtner, B. Steigenberger, A. Holovan, F. Streshnev, S. Schneider, M. Müller, T. Carell

Angew. Chem. Int. Ed. 2024, 10.1002/anie.202405161

"Efficient Tandem Cu-Catalyzed Click Synthesis of Multi-Sugar-Modified Oligonucleotides"

 Link to publication

299

E. Węgrzyn, I. Mejdrová, F. Müller, M. Nainytė, L. Escobar, T. Carell

Angew. Chem. Int. Ed. 2024, 10.1002/anie.202319235

"RNA-Templated Peptide Bond Formation Promotes L-Homochirality"

 Link to publication

298

P. Karousi, M. Samiotaki, M. Makridakis, J. Zoidakis, D. C. Sideris, A. Scorilas, T. Carell, C. K. Kontos

Funct. Integr. Genomics. 2023, 10.1007/s10142-023-01272-0

"3′-tRF-Cys^GCA overexpression in HEK-293 cells alters the global expression profile and modulates cellular processes and pathways."

 Link to publication

297

A. Pichler, M. Hillmeier, M. Heiss, E. Peev, S. Xefteris, B. Steigenberger, I. Thoma, M. Müller, M. Borsò, A. Imhof, T. Carell

J.Am.Chem.Soc. 2023, 10.1021/jacs.3c10075

"Synthesis and Structure Elucidation of Glutamyl-Queuosine."

 Link to publication

296

E.S. Schönegger, A. Crisp, M. Radukic, J. Burmester, T. Frischmuth, T. Carell

ChemBioChem 2023, 10.1002/cbic.202300701

"Orthogonal end labelling of oligonucleotides via dual incorporation of Click reactive NTP analogues."

 Link to publication

295

F. Xu, S. Wiedemann, J. Feldmann, S. Becker, T. Carell

ChemistryEurope 2023, 10.1002/ceur.202300057

"An Aminoisoxazole-Based Proto-RNA."

 Link to publication

294

M. Witzenberger, S. Burczyk , D. Settele, W. Mayer, L. M. Welp, M. Heiss, M. Wagner, T. Monecke, R. Janowski, T. Carell, H. Urlaub, S. M. Hauck, A. Voigt, D. Niessing

Nucleic Acids Res. 2023, 10.1093/nar/gkad565

"Human TRMT2A methylates tRNA and contributes to translation fidelity."

 Link to publication

293

A. Nieborak, S. Lukauskas, J. Capellades, P. Heyn, G. S. Santos, K. Motzler, A. Zeigerer, R. Bester, U. Protzer, F. Schelter, M. Wagner, T. Carell, A. Hruscha, B. Schmid, O. Yanes, R. Schneider

Mol. Metab. 2023, 10.1016/j.molmet.2023.101748

"Depletion of pyruvate kinase (PK) activity causes glycolytic intermediate imbalances and reveals a PK-TXNIP regulatory axis"

 Link to publication

292

J. Feldmann, M. K. Skaanning, M. Lommel, T. Kernmayr, P. Mayer, T. Carell

ChemistryEurope. 2023, 10.1002/ceur.202300013

"A Unifying Concept for the Prebiotic Formation of RNA Pyrimidine Nucleosides"

 Link to publication

291

J. N. Singer, F. M. Müller, E. Węgrzyn, C. Hölzl, H. Hurmiz, C. Liu, L. Escobar, T. Carell

Angew. Chem. Intl. Ed. 2023, 10.1002/anie.202302360

"Loading of Amino Acids onto RNA in a Putative RNA-Peptide World"

 Link to publication

290

N. Kuhl, A. Linder, N. Philipp, D. Nixdorf, H. Fischer, S. Veth, G. Kuut, T. T. Xu, S. Theurich, T. Carell, M. Subklewe, V. Hornung

EMBO Rep. 2023, 10.15252/embr.202255536

"STING agonism turns human T cells into interferon-producing cells but impedes their functionality"

 Link to publication

289

B. Searle, M. Müller, T. Carell, A. Kellett

Angew. Chem. Intl. Ed. 2022, 10.1002/anie.202215704

"Third Generation Sequencing of Epigenetic DNA"

 Link to publication

288

L. Montiel, F. Spada, A. Crisp, S. Serdjukow, T. Carell, T. Frischmuth

Chem. Eur. J. 2022, 10.1002/chem.202202633

"Divergent Synthesis of Ultrabright and Dendritic Xanthenes for Enhanced Click Chemistry-Based Bioimaging"

 Link to publication

287

E.S. Schönegger, A. Crisp, M. Müller, J. Fertl, S. Serdjukow, S. Croce, M. Kollaschinski, T. Carell, T. Frischmuth

Bioconjugate Chem. 2022, 10.1021/acs.bioconjchem.2c00353

"Click Chemistry Enables Rapid Amplification of Full-Length Reverse Transcripts for Long-Read Third Generation Sequencing"

 Link to publication

286

F. Xu, A. Crisp, T. Schinkel, R. C. A. Dubini, S. Hübner, S. Becker, F. Schelter, P. Rovó, T. Carell

Angew. Chem. Intl. Ed. 2022, 10.1002/anie.202211945

"Isoxazole Nucleosides as Building Blocks for a Plausible Proto-RNA."

 Link to publication

285

M. Arroyo, F. D. Hastert, A. Zhadan, F. Schelter, S. Zimbelmann, C. Rausch, A. K. Ludwig, T. Carell, M. C.Cardoso

Nat. Commun. 2022, 10.1038/s41467-022-32799-8

"Isoform-specific and ubiquitination dependent recruitment of Tet1 to replicating heterochromatin modulates methylcytosine oxidation."

 Link to publication

284

B. I. Patel, M. Heiss, A. Samel-Pommerencke, T. Carell, A. E. Ehrenhofer-Murray

Biochem Biophys Res Commun. 2022, 10.1016/j.bbrc.2022.07.104

"Queuosine salvage in fission yeast by Qng1-mediated hydrolysis to queuine."

 Link to publication

283

S. Stazzoni, D. F. R. Böhmer, F. Hernichel, D. Özdemir, A. Pappa, D. Drexler, S. Bauernfried, G. Witte, M. Wagner, S. Veth, K.-P. Hopfner, V. Hornung, L. M. König, T. Carell

Angew. Chem. Int. Ed. 2022, 10.1002/anie.202207175

"Novel Poxin Stable cGAMP-Derivatives Are Remarkable STING Agonists."

 Link to publication

282

F. R. Traube, M. Stern, A. J. Tölke, M. Rudelius, E. Mejías-Pérez, N. Raddaoui, B. M. Kümmerer, C. Douat, F. Streshnev, M. Albanese, P. R. Wratil, Y. V. Gärtner, M. Nainytė, G. Giorgio, S. Michalakis, S. Schneider, H. Streeck, M. Müller, O. T. Keppler, T. Carell

Angew. Chem. Int. Ed. 2022, 10.1002/anie.202204556

"Suppression of SARS-CoV-2 Replication with Stabilized and Click-Chemistry modified siRNAs."

 Link to publication

281

M. Czuppa, A. Dhingra, Q. Zhou, C. Schludi, L. König, E. Scharf, D. Farny, A. Dalmia, J. Täger, M. Castillo-Lizardo, E. Katona, K. Mori, T. Aumer, F. Schelter, M. Müller, T. Carell, T. Kalliokoski, J. Messinger, P. Rizzu, P. Heutink, D. Edbauer

Cell Rep. 2022, 10.1016/j.celrep.2022.110913

"Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G₄C₂)_n expression in C9orf72 ALS/FTD."

 Link to publication

280

R. C. A. Dubini, E. Korytiaková, T. Schinkel, P. Heinrichs, T. Carell, P. Rovó

ACS Phys. Chem Au 2022, 10.1021/acsphyschemau.1c00050

"¹H NMR Chemical Exchange Techniques Reveal Local and Global Effects of Oxidized Cytosine Derivatives."

 Link to publication

279

F. Müller, L. Escobar, F. Xu, E. Węgrzyn, M. Nainytė, T. Amatov, C.-Y. Chan, A. Pichler, T. Carell

Nature 2022, 10.1038/s41586-022-04676-3

"A prebiotically plausible scenario of an RNA–peptide world."

 Link to publication

278

F. R. Traube, N. F. Brás, W. P. Roos, C. C. Sommermann, T. Diehl, R. J. Mayer, A. R. Ofial, M. Müller, H. Zipse, T. Carell

Chemistry 2022, 10.1002/chem.202200640

"Epigenetic anti-cancer treatment with a stabilized carbocyclic Decitabine analogue."

 Link to publication

277

S. Veth, A. Fuchs, D. Özdemir, C. Dialer, D. J. Drexler, F. Knechtel, G. Witte, K.-P. Hopfner, T. Carell, E. Ploetz

Chembiochem. 2022, 10.1002/cbic.202200005

"Chemical synthesis of the fluorescent, cyclic dinucleotides cthGAMP."

 Link to publication

276

H. Panosyan, F. R. Traube, C. Brandmayr, M. Wagner, T. Carell

Extremophiles 2022, 10.1007/s00792-022-01258-z

"tRNA modification profiles in obligate and moderate thermophilic bacilli."

 Link to publication

275

M.A. Margreiter, M. Witzenberger, Y. Wasser, E. Davydova, R. Janowski, J. Metz, P. Habib, S.E.M. Sahnoun, C. Sobisch, B. Poma, O. Palomino-Hernandez, M. Wagner, T. Carell, N. Jon Shah, J.B. Schulz, D. Niessing, A. Voigt, G. Rossetti

Comput. Struct. Biotechnol. J. 2022, 10.1016/j.csbj.2021.12.029

"Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death."

 Link to publication